Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813582 | 0.94 | CHRM2 (0.34) | NAAATSHRLMNA | |
| SCHEMBL10957842 | 0.78 | NAAA (0.43) | NAAAEPHX1TSHREPHX2HCAR2 | |
| SCHEMBL11444732 | 0.78 | NAAA (0.43) | NAAAEPHX1TSHREPHX2HCAR2 | |
| SCHEMBL473289 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL104550 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL1416698 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL1837930 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL35190 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL76043 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 | |
| SCHEMBL473104 | 0.78 | NAAA (0.61) | NAAAEPHX1TSHRHTR2CPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| US-4772708-A | STABILIZERS FOR POLYMERS | AUSIMONT S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |