Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813875 | 1.00 | SLC2A1 (0.50) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813944 | 1.00 | SLC2A1 (0.50) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813982 | 1.00 | SLC2A1 (0.50) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813952 | 1.00 | SLC2A1 (0.50) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813900 | 1.00 | SLC2A1 (0.50) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813948 | 0.96 | SLC2A1 (0.47) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813937 | 0.96 | SLC2A1 (0.47) | SLC2A1ADRB3ADRB2ADRB1CYP2D6 | |
| SCHEMBL9813945 | 0.85 | TAAR1 (0.40) | ADRB3ADRB2ADRB1CYP2D6ADRA1A | |
| SCHEMBL9813912 | 0.85 | MAOB (0.42) | ADRB3ADRB2ADRB1CYP2D6ADRA1A | |
| SCHEMBL9813921 | 0.85 | MAOB (0.42) | ADRB3ADRB2ADRB1CYP2D6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017619-A | Anitdiabetic | HOFFMANN-LA ROCHE INC. (US) | 1991-05-21 | — | — | US | disclosed |