SCHEMBL9814366

SCHEMBL9814366

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CD209 Q9NNX6 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
SYNJ2 O15056 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145406 1.00 TYR (0.37) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL8720844 1.00 TYR (0.37) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL28475368 0.89 TYR (0.40) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL1422033 0.84 L3MBTL1 (0.38) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL1422035 0.84 L3MBTL1 (0.38) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL25250403 0.83 PPARG (0.40) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL11757443 0.81 L3MBTL1 (0.41) TYRPPARGPPARDPPARAL3MBTL1
SCHEMBL11755320 0.81 L3MBTL1 (0.41) TYRPPARGPPARDPPARAL3MBTL1
Lactitol SCHEMBL9098934 0.80 PPARG (0.40) TYRPPARGPPARDPPARAL3MBTL1
Lactitol SCHEMBL4398901 0.80 PPARG (0.40) TYRPPARGPPARDPPARAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249364-B1 DUAL CATALYST SEQUENTIAL METHOD FOR PRODUCTION OF SORBITOL FROM HYDROLYZED STARCH SOLUTION PFIZER INC. (US) 1991-06-12 EP disclosed
EP-0249364-A2 Dual catalyst sequential method for production of sorbitol from hydrolyzed starch solution PFIZER INC. (US) 1987-12-16 EP disclosed
US-4694113-A HYDROGENATION PFIZER INC. (US) 1987-09-15 US disclosed