Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764557 | 0.86 | PTPN1 (0.39) | CYP3A4CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9814446 | 0.83 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9814383 | 0.78 | SNCA (0.47) | CYP3A4SNCAHPGDALDH1A1TAS1R3 | |
| SCHEMBL1470081 | 0.75 | MGLL (0.46) | CYP3A4CYP2C19SNCAALDH1A1TAS1R3 | |
| SCHEMBL7769255 | 0.74 | SNCA (0.44) | CYP3A4CYP2D6CYP2C9CYP2C19SNCA | |
| SCHEMBL26417020 | 0.73 | SNCA (0.49) | CYP3A4CYP2D6CYP2C9CYP2C19SNCA | |
| SCHEMBL26810445 | 0.73 | SNCA (0.49) | CYP3A4SNCAALDH1A1TAS1R3TAS1R1 | |
| Propene SCHEMBL1077347 | 0.72 | MGLL (0.43) | CYP2C19SNCAALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL29030403 | 0.72 | SNCA (0.47) | CYP3A4SNCAALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9814412 | 0.72 | TDP1 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211104-B1 | COMPOSITES | Nippon Shiken Dental Co., Ltd. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4705836-A | Polymerization composition containing vinyl benzoic acid or a derivative thereof and a vinyl compound | NIPPON SHIKEN DENTAL CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0211104-A2 | Composites | Nippon Shiken Dental Co., Ltd. (JP) | 1987-02-25 | — | — | EP | disclosed |