Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.88 |
| ▸ | ESR1 | P03372 | 2/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.88 |
| ▸ | TACR2 | P21452 | 2/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.88 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | SHBG | P04278 | 1/20 | 0.88 |
| ▸ | TP53 | P04637 | 1/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.88 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.88 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.88 |
| ▸ | HTR2C | P28335 | 1/20 | 0.88 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227876 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL982001 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28177799 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL984111 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL981893 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL982373 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7934900 | 1.00 | PTGS2 (0.88) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL982418 | 0.98 | PTGS2 (0.84) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7253630 | 0.98 | PTGS2 (0.84) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL19497894 | 0.96 | PTGS2 (0.81) | PTGS2ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275405-B1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | ASAHI CHEMICAL IND (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-2792673-B1 | Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds | ASAHI CHEMICAL IND (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9637445-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-2147909-B1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-12-14 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| CN-103467730-B | Carbamate compounds | Asahi Kasei Chemical K. K. (JP) | 2015-12-23 | — | — | CN | disclosed |
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| EP-2213658-B1 | METHOD FOR PRODUCTION OF ISOCYANATE AND AROMATIC HYDROXY COMPOUND | ASAHI KASEI CHEMICALS CORP (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-9056819-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-16 | — | — | US | disclosed |
| US-5075032-A | Electrooptics, switches, displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-12-24 | — | — | US | disclosed |
| US-4886620-A | Smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0174191-B1 | LIQUID CRYSTAL COMPOUND HAVING METHYLENEOXY GROUP AND COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1988-07-27 | — | — | EP | disclosed |
| US-4751019-A | OPTICAL ACTIVITY | CHISSO CORPORATION (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0233267-A1 | SMECTIC CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1987-08-26 | — | — | EP | disclosed |
| US-4668427-A | LIGHT SWITCHING ELEMENT | CHISSO CORPORATION (JP) | 1987-05-26 | — | — | US | disclosed |
| WO-1987001717-A2 | SMECTIC CYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-03-26 | — | — | WO | disclosed |
| EP-0174191-A1 | Liquid crystal compound having methyleneoxy group and composition containing same | Chisso Corporation (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4487954-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4405488-A | LOW VISCOSITY, HIGH TRANSPARENT POINT | CHISSO CORPORATION (JP) | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | PAH, APEH, CPS1 | PTGS2 1309/4885ESR1 1799/4885ADRA2A 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.