SCHEMBL9814486

SCHEMBL9814486

O=C(O)CCCN1C(=O)C(=CC=C2SCCN2CCCS(=O)(=O)O)SC1=S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.55
MAPT P10636 10/20 0.55
MEN1 O00255 9/20 0.55
ALDH1A1 P00352 6/20 0.55
L3MBTL1 Q9Y468 5/20 0.55
USP2 O75604 4/20 0.55
MCOLN3 Q8TDD5 2/20 0.55
TNNI3 P19429 2/20 0.55
TNNT2 P45379 2/20 0.55
TNNC1 P63316 2/20 0.55
PPARG P37231 1/20 0.55
NCOA2 Q15596 1/20 0.55
NCOA1 Q15788 1/20 0.55
POLB P06746 6/20 0.53
RAB9A P51151 5/20 0.53
NPC1 O15118 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MAPK1 P28482 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9814495 0.95 KMT2A (0.56) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL9491695 0.90 KMT2A (0.69) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL9491697 0.90 KMT2A (0.69) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL11687174 0.85 MEN1 (0.65) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL11687189 0.85 MEN1 (0.65) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL9814494 0.80 MEN1 (0.47) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL10778496 0.79 KMT2A (0.73) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL10778499 0.79 KMT2A (0.73) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL9189220 0.79 ALDH1A1 (0.67) KMT2AMAPTMEN1ALDH1A1L3MBTL1
SCHEMBL9189215 0.79 ALDH1A1 (0.67) KMT2AMAPTMEN1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213963-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (2) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP claimed
US-4680255-A Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US claimed
EP-0213963-A2 Silver halide photographic emulsions with novel grain faces (2) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-03-11 EP claimed