Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.78 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | ACACB | O00763 | 1/20 | 0.59 |
| ▸ | ACACA | Q13085 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20081140 | 1.00 | SRD5A2 (0.78) | SRD5A2PARP10ACACBACACAPOLB | |
| SCHEMBL9452100 | 0.96 | SRD5A2 (0.71) | SRD5A2PARP10ACACBACACAPOLB | |
| SCHEMBL12757139 | 0.96 | SRD5A2 (0.71) | SRD5A2PARP10ACACBACACAPOLB | |
| SCHEMBL12757137 | 0.94 | SRD5A2 (0.69) | SRD5A2PARP10ACACBACACAPOLB | |
| SCHEMBL13599782 | 0.94 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEERCC5 | |
| SCHEMBL1082112 | 0.94 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEERCC5 | |
| SCHEMBL9536469 | 0.94 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEERCC5 | |
| SCHEMBL2866068 | 0.94 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEERCC5 | |
| SCHEMBL235530 | 0.94 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEERCC5 | |
| SCHEMBL234249 | 0.91 | SRD5A2 (0.84) | SRD5A2PARP10POLBELANEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145975-B1 | AMINE-DERIVATISED POLYARYLETHERKETONE COPOLYMERS | KETONEX LTD (GB) | 2021-03-17 | — | — | EP | disclosed |
| EP-2451858-B1 | METHOD FOR PREPARING POLY (ETHER KETONE KETONES) | KETONEX LTD (GB) | 2020-10-28 | — | — | EP | disclosed |
| EP-3145980-B1 | PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMER AND COPOLYMERS THEREOF | CYTEC IND INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-10450408-B2 | Method for making polyarylaliphaticetherketone polymers and copolymers thereof | KETONEX LIMITED (GB) | 2019-10-22 | — | — | US | disclosed |
| EP-3145974-B1 | METHOD FOR MAKING PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMERS AND COPOLYMERS THEREOF | KETONEX LTD (GB) | 2018-04-25 | — | — | EP | disclosed |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | OXFORD PERFORMANCE MATERIALS, INC | 2017-09-07 | — | — | US | disclosed |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | OXFORD PERFORMANCE MATERIALS, INC | 2017-09-07 | — | — | US | disclosed |
| US-9683079-B2 | Particulate amine-functionalized polyaryletherketone polymer and copolymers thereof | KETONEX LIMITED (GB) | 2017-06-20 | — | — | US | disclosed |
| US-9683079-B2 | Particulate amine-functionalized polyaryletherketone polymer and copolymers thereof | KETONEX LIMITED (GB) | 2017-06-20 | — | — | US | disclosed |
| US-20170107323-A1 | METHOD FOR MAKING PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMERS AND COPOLYMERS THEREOF | OXFORD PERFORMANCE MATERIALS, INC | 2017-04-20 | — | — | US | disclosed |
| US-20150337082-A1 | PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMER AND COPOLYMERS THEREOF | KETONEX LIMITED (GB) | 2015-11-26 | — | — | US | disclosed |
| US-20150337082-A1 | PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMER AND COPOLYMERS THEREOF | KETONEX LIMITED (GB) | 2015-11-26 | — | — | US | disclosed |
| US-9023468-B2 | Method for preparing poly (ether ketone ketones) | KETONEX LIMITED (GB) | 2015-05-05 | — | — | US | disclosed |
| US-9023468-B2 | Method for preparing poly (ether ketone ketones) | KETONEX LIMITED (GB) | 2015-05-05 | — | — | US | disclosed |
| US-20120263953-A1 | METHOD FOR PREPARING POLY (ETHER KETONE KETONES) | KETONEX LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
| US-20120263953-A1 | METHOD FOR PREPARING POLY (ETHER KETONE KETONES) | KETONEX LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
| WO-2011004164-A2 | METHOD FOR PREPARING POLY (ETHER KETONE KETONES) | KETONEX LIMITED (GB) | 2011-01-13 | — | — | WO | disclosed |
| EP-0262919-B1 | PREPARATION OF ARYL CARBONYL COMPOUNDS | RAYCHEM LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4898983-A | FRIEDEL-CRAFTS PROCESS; LEWIS ACIDS, BY-PRODUCT INHIBITION; ACID HALIDES, ACTIVE HYDROGEN AROMATIC COMPONENTS; CONTROLLING AGENTS | RAYCHEM LIMITED (GB) | 1990-02-06 | — | — | US | disclosed |
| EP-0262919-A2 | Preparation of aryl carbonyl compounds | RAYCHEM LIMITED (GB) | 1988-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450408-B2 | Method for making polyarylaliphaticetherketone polymers and copolymers thereof | DAO, DCXR, LOX | SRD5A2 480/4885PARP10 1604/4885ACACB 676/4885 |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | COASY, FRK, PBK | SRD5A2 582/4885PARP10 635/4885ACACB 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.