⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19274682 | 1.00 | — | — | |
| SCHEMBL96734 | 0.85 | — | — | |
| SCHEMBL5068776 | 0.85 | — | — | |
| SCHEMBL2394322 | 0.83 | FAAH (0.52) | — | |
| SCHEMBL8009240 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL3945045 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL76817 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL6473139 | 0.81 | FAAH (0.56) | — | |
| SCHEMBL2395653 | 0.81 | FAAH (0.56) | — | |
| SCHEMBL3039634 | 0.81 | FAAH (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806580-A | 12-O-fatty acid ester oleanolic acid compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-03-17 | — | — | CN | claimed |
| EP-0657166-B1 | Combination containing a quinoxaline and a nucleoside | AVENTIS PHARMA GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6369057-B1 | VIRICIDES, IN PARTICULAR AGAINST RETROVIRUSES, HUMAN IMMUNODEFICIENCY VIRUS (HIV) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | claimed |
| EP-0509398-B1 | Quinoxalines, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-19 | — | — | EP | claimed |
| EP-0728481-A2 | Use of quinoxaline and protease inhibitors in a composition for the treatment of AIDS and/or HIV infections | BAYER AG (DE) | 1996-08-28 | — | — | EP | claimed |
| EP-0509398-A1 | Quinoxalines, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | claimed |
| US-20240158446-A1 | CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-16 | — | — | US | disclosed |
| WO-2024101386-A1 | CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS | 中外製薬株式会社 | 2024-05-16 | — | — | WO | disclosed |
| WO-2024101402-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS | 中外製薬株式会社 | 2024-05-16 | — | — | WO | disclosed |
| US-20240148821-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-09 | — | — | US | disclosed |
| WO-2024080333-A1 | METHOD FOR PRODUCING N-SUBSTITUTED AMINO ACID RESIDUE-CONTAINING CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2024-04-18 | — | — | WO | disclosed |
| US-20240124517-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-18 | — | — | US | disclosed |
| CN-114466893-B | Polyester film for window covering, and polyester film laminate for window covering | 三菱化学株式会社 | 2024-03-01 | — | — | CN | disclosed |
| EP-0138523-A1 | Penicillin derivatives and process for preparing the same (11111) | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4508914-A | INTERMEDIATES FOR PYRETHROID INSECTICIDES | DYNAMIT NOBEL AG (DE) | 1985-04-02 | — | — | US | disclosed |
| US-4492799-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |
| US-4424369-A | Substituted pyran-2-ones | DYNAMIT NOBEL AG (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4348535-A | Substituted lactones and processes for their preparation | DYNAMIT NOBEL AG (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4291057-A | INSECTICIDES AND MITICIDES | UNION CARBIDE CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |