Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835883 | 0.92 | CDK1 (0.55) | CDK1GAANPC1RAB9ACYP1A2 | |
| SCHEMBL11385667 | 0.86 | CDK1 (0.57) | CDK1GAACYP1A2MAPTTP53 | |
| SCHEMBL9826126 | 0.85 | GAA (0.50) | CDK1GAANPC1RAB9ACYP1A2 | |
| SCHEMBL8507050 | 0.85 | CDK1 (0.56) | CDK1GAACYP1A2MAPTTP53 | |
| SCHEMBL10395502 | 0.85 | CDK1 (0.56) | CDK1GAACYP1A2MAPTTP53 | |
| SCHEMBL1405765 | 0.83 | GAA (0.59) | CDK1GAANPC1CYP1A2MAPT | |
| SCHEMBL10396053 | 0.83 | CDK1 (0.62) | CDK1GAANPC1CYP1A2MAPT | |
| SCHEMBL8782215 | 0.83 | CDK1 (0.62) | CDK1GAACYP1A2MAPTTP53 | |
| SCHEMBL5846414 | 0.83 | CDK1 (0.62) | CDK1GAACYP1A2MAPTTP53 | |
| SCHEMBL18932247 | 0.83 | CDK1 (0.51) | CDK1GAACYP1A2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812441-A | Hypocholesterolemically active protein derived from streptococcus | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1989-03-14 | — | — | US | claimed |
| EP-0162723-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4981509-A | Plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4871847-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4849010-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4812441-A | Hypocholesterolemically active protein derived from streptococcus | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4812441-A | Hypocholesterolemically active protein derived from streptococcus | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4724039-A | RICE CROP | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4710221-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0162723-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |