Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 4/20 | 0.47 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20912155 | 0.84 | PER2 (0.44) | PER2CRY2DPP4 | |
| SCHEMBL2602303 | 0.81 | PER2 (0.44) | PER2CRY2DPP4ALDH1A1PIK3CD | |
| SCHEMBL10121114 | 0.79 | PER2 (0.50) | PER2CRY2DPP4PIK3CD | |
| SCHEMBL19872811 | 0.79 | PER2 (0.43) | PER2CRY2DPP4ALDH1A1PIK3CD | |
| SCHEMBL19364816 | 0.78 | PER2 (0.42) | PER2CRY2DPP4 | |
| SCHEMBL26661693 | 0.77 | PER2 (0.44) | PER2CRY2DPP4 | |
| SCHEMBL596921 | 0.77 | PER2 (0.38) | PER2CRY2ALDH1A1PIK3CDMAPT | |
| SCHEMBL133648 | 0.77 | CYP2D6 (0.36) | ALDH1A1 | |
| SCHEMBL8112323 | 0.76 | PER2 (0.41) | PER2CRY2DPP4 | |
| SCHEMBL11831972 | 0.76 | PER2 (0.32) | PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864026-A | Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d | HULS AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0280781-B1 | PROCESS FOR THE PREPARATION OF N-ALKYL-N'-METHYL-CYCLIC UREAS, ESPECIALLY N,N'-DIMETHYLCYCLIC UREAS | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-4864026-A | Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d | HULS AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0280781-A1 | Process for the preparation of N-alkyl-N'-methyl-cyclic ureas, especially N,N'-dimethylcyclic ureas | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |