Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143478 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL10560584 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL22960669 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL30552169 | 0.79 | APP (0.40) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL28669974 | 0.79 | APP (0.40) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL9815134 | 0.77 | KDM4E (0.47) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL10053401 | 0.76 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL12156952 | 0.75 | KDM4E (0.51) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL2616778 | 0.74 | APP (0.67) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL9580861 | 0.73 | ESR1 (0.62) | ALDH1A1MEN1MAPTKMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172298-B1 | METHOD FOR MAKING THIOETHER(BISPHTHALIMIDE)S | GENERAL ELECTRIC COMPANY (US) | 1991-09-11 | — | — | EP | claimed |
| EP-0108682-B1 | SOLVENT FREE PREPARATION OF DIARYLTHIOETHERS | GENERAL ELECTRIC COMPANY (US) | 1988-01-27 | — | — | EP | claimed |
| US-4625037-A | Method for making thioether(bisphthalimide)s | GENERAL ELECTRIC COMPANY (US) | 1986-11-25 | — | — | US | claimed |
| EP-0172298-A2 | Method for making thioether(bisphthalimide)s | GENERAL ELECTRIC COMPANY (US) | 1986-02-26 | — | — | EP | claimed |
| US-4499285-A | REACTING AN ALKALI METAL SULFIDE WITH HALOGEN, IMIDE, OR ANHYDRIDE SUBSTITUTED AROMATIC COMPOUND IN PRESENCE OF PHASE TRANSFER COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1985-02-12 | — | — | US | claimed |
| EP-0108682-A1 | Solvent free preparation of diarylthioethers | GENERAL ELECTRIC COMPANY (US) | 1984-05-16 | — | — | EP | claimed |
| US-4054584-A | ALKALI METAL SULFIDES | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | claimed |
| EP-0172298-B1 | METHOD FOR MAKING THIOETHER(BISPHTHALIMIDE)S | GENERAL ELECTRIC COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0108682-B1 | SOLVENT FREE PREPARATION OF DIARYLTHIOETHERS | GENERAL ELECTRIC COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |
| US-4625037-A | Method for making thioether(bisphthalimide)s | GENERAL ELECTRIC COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| US-4622324-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVES | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1986-11-11 | — | — | US | disclosed |
| EP-0172298-A2 | Method for making thioether(bisphthalimide)s | GENERAL ELECTRIC COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4535158-A | CHEMICXAL INTERMEDIATES FOR CARDIOTONIC AGENTS | DR. WILLMAR SCHWABE GMBH & CO. | 1985-08-13 | — | — | US | disclosed |
| EP-0126252-A1 | Sulfur-containing aromatic compositions and methods for their preparation and use | GENERAL ELECTRIC COMPANY (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4479951-A | CORONARY DIESASE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1984-10-30 | — | — | US | disclosed |
| EP-0108682-A1 | Solvent free preparation of diarylthioethers | GENERAL ELECTRIC COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |
| US-4413122-A | Optionally N-substituted aminodesoxy-1.4;3.6-dianhydrohexitol derivatives | FA. WILMAR SCHWABE GMBH & CO. (DE) | 1983-11-01 | — | — | US | disclosed |
| US-4363805-A | TREATMENT OF CORONARY DISEASE | FIRMA WILLMAR SCHWABE (DE) | 1982-12-14 | — | — | US | disclosed |
| US-4054584-A | ALKALI METAL SULFIDES | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3989712-A | Thio-bis(phthalimides) | GENERAL ELECTRIC COMPANY (US) | 1976-11-02 | — | — | US | disclosed |