Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863824 | 0.82 | HPGD (0.43) | PPARDCYP3A4FAAHHPGDSMN1; SMN2 | |
| SCHEMBL2488249 | 0.79 | — | — | |
| SCHEMBL11294135 | 0.78 | LPAR3 (0.52) | FAAHLPAR3LPAR2 | |
| SCHEMBL27787465 | 0.77 | — | — | |
| SCHEMBL575221 | 0.77 | — | — | |
| SCHEMBL5488995 | 0.75 | MEN1 (0.39) | PPARDCYP3A4TSHRHPGDSMN1; SMN2 | |
| SCHEMBL6235884 | 0.73 | TSHR (0.38) | PPARDTSHR | |
| SCHEMBL7229 | 0.73 | PPARD (0.48) | PPARDFAAHLPAR3LPAR2 | |
| SCHEMBL15976586 | 0.73 | — | — | |
| SCHEMBL12197583 | 0.73 | PPARD (0.43) | PPARDTSHRFAAHSMN1; SMN2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068351-A | PROCESS FOR THE PREPARATION OF N OCTAHYDROPENTA (6) PYRROLE CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0257380-B1 | PROCESS FOR THE PREPARATION OF THIOPHOSPHINIC ACID CHLORIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0135182-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| US-4751028-A | Process for the preparation of thiophosphinic chlorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-14 | — | — | US | disclosed |
| EP-0135183-B1 | PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING CARBOXYLIC ACID AMIDE GROUPS, ESPECIALLY OF PEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-30 | — | — | EP | disclosed |
| EP-0257380-A2 | Process for the preparation of thiophosphinic acid chlorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0056618-B1 | PROCESS FOR PREPARING COMPOUNDS THAT CONTAIN CARBOXYAMIDE GROUPS, ESPECIALLY PEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0074582-B1 | PROCESS FOR PREPARING DIALKYLPHOSPHINIC-ACID HALIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4481151-A | Process for the preparation of dialkylphosphinic acid halides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-06 | — | — | US | disclosed |
| US-4426325-A | Process for the preparation of compounds containing carboxylic acid amide groups, in particular or peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0074582-A1 | Process for preparing dialkylphosphinic-acid halides | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-23 | — | — | EP | disclosed |
| EP-0056618-A1 | Process for preparing compounds that contain carboxyamide groups, especially peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-28 | — | — | EP | disclosed |