Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17198831 | 0.82 | CA2 (0.37) | TSHRTDP1PPARD | |
| SCHEMBL84287 | 0.76 | — | — | |
| SCHEMBL17198819 | 0.76 | PPARD (0.32) | PPARD | |
| SCHEMBL575282 | 0.73 | — | — | |
| SCHEMBL9815249 | 0.73 | PPARD (0.39) | TSHRPPARD | |
| SCHEMBL29207923 | 0.73 | — | — | |
| SCHEMBL18309148 | 0.73 | — | — | |
| SCHEMBL25254620 | 0.69 | — | — | |
| SCHEMBL4820636 | 0.69 | — | — | |
| SCHEMBL14169001 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068351-A | PROCESS FOR THE PREPARATION OF N OCTAHYDROPENTA (6) PYRROLE CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | claimed |
| EP-0156280-B1 | PROCESS FOR THE PREPARATION OF PEPTIDE INTERMEDIATES POOR IN RACEMATES, BELONGING TO GONADORELIN AND GONADORELIN ANALOGUES, THEIR SYNTHESIS AND INTERMEDIATES OBTAINED BY THIS PROCESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-07 | — | — | EP | claimed |
| EP-0135182-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | claimed |
| US-4691008-A | COUPLING A URETHANE-BLOCKED TRIPEPTIDE AND A PEPTIDE WITH A FREE AMINE USING A CONDENSATION AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | claimed |
| EP-0156280-A2 | Process for the preparation of peptide intermediates poor in racemates, belonging to gonadorelin and gonadorelin analogues, their synthesis and intermediates obtained by this process | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-02 | — | — | EP | claimed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | claimed |
| US-12559484-B2 | Route for constructing chiral fragment of fezolinetant, intermediate thereof, and preparation method therefor | SHENZHEN HWAGEN PHARMACEUTICAL CO., LTD. (CN) | 2026-02-24 | — | — | US | disclosed |
| US-20260015345-A1 | ROUTE FOR CONSTRUCTING CHIRAL FRAGMENT OF FEZOLINETANT, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR | SHENZHEN HWAGEN PHARMACEUTICAL CO., LTD. (CN) | 2026-01-15 | — | — | US | disclosed |
| US-12421193-B2 | GPR52 modulators and methods of use | NEUROCRINE BIOSCIENCES, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| EP-4608507-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | Neurocrine Biosciences, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| US-12383536-B2 | CRF receptor antagonists and methods of use | NEUROCRINE BIOSCIENCES, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| EP-4069697-B1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES INC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2025092756-A1 | LIPID COMPOUND AND COMPOSITION THEREOF | GUANGZHOU RIBOBIO CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0135183-A2 | Process for the preparation of compounds containing carboxylic acid amide groups, especially of peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4481151-A | Process for the preparation of dialkylphosphinic acid halides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-06 | — | — | US | disclosed |
| EP-0117447-A1 | Cyclic peptides with somatostatin activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-05 | — | — | EP | disclosed |
| US-4426325-A | Process for the preparation of compounds containing carboxylic acid amide groups, in particular or peptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0074582-A1 | Process for preparing dialkylphosphinic-acid halides | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-23 | — | — | EP | disclosed |
| US-4138433-A | Process for preparing 1,2-oxa-phospholanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015345-A1 | ROUTE FOR CONSTRUCTING CHIRAL FRAGMENT OF FEZOLINETANT, INTERMEDIATE THEREOF, AND PREPARATION METHOD THEREFOR | CYP19A1, CYP4F11, CYP11B1 | TSHR 357/4885TP53 4400/4885TDP1 2704/4885 |
| US-12383536-B2 | CRF receptor antagonists and methods of use | CRHR1, CRHR2, MC2R | TSHR 267/4885TP53 4768/4885TDP1 4426/4885 |
| US-12559484-B2 | Route for constructing chiral fragment of fezolinetant, intermediate thereof, and preparation method therefor | PTGIS, TMEM109, CYP11B1 | TSHR 333/4885TP53 4474/4885TDP1 3061/4885 |
| US-12421193-B2 | GPR52 modulators and methods of use | GPR52, GPR68, GPR35 | TSHR 725/4885TP53 4535/4885TDP1 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.