Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9815284 | 0.99 | OPRD1 (0.74) | OPRD1NPC1RAB9AOPRK1PARP1 | |
| SCHEMBL9815297 | 0.86 | OPRD1 (0.71) | OPRD1OPRK1PARP1 | |
| SCHEMBL9815271 | 0.85 | OPRD1 (0.70) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9815305 | 0.85 | OPRD1 (0.70) | OPRD1OPRK1PARP1 | |
| SCHEMBL9699133 | 0.84 | OPRD1 (1.00) | OPRD1NPC1OPRK1 | |
| Hydrochloric Acid SCHEMBL9815366 | 0.83 | OPRD1 (0.68) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9815363 | 0.83 | OPRD1 (0.68) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9699115 | 0.83 | OPRD1 (0.98) | OPRD1OPRK1 | |
| SCHEMBL10434789 | 0.83 | OPRD1 (0.67) | OPRD1NPC1RAB9AOPRK1PARP1 | |
| SCHEMBL10434623 | 0.83 | OPRD1 (0.73) | OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232989-B1 | ISOQUINOLINE DERIVATIVES | Dr. Lo. Zambeletti S.p.A. (IT) | 1991-08-21 | — | — | EP | claimed |
| EP-0232989-B1 | ISOQUINOLINE DERIVATIVES | Dr. Lo. Zambeletti S.p.A. (IT) | 1991-08-21 | — | — | EP | disclosed |