Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL10361050 | 1.00 | — | — | |
| SCHEMBL94573 | 0.91 | — | — | |
| SCHEMBL11014587 | 0.80 | — | — | |
| SCHEMBL2958233 | 0.66 | LMNA (0.36) | — | |
| SCHEMBL949424 | 0.66 | LMNA (0.36) | — | |
| SCHEMBL3041976 | 0.61 | — | — | |
| SCHEMBL5864280 | 0.59 | — | — | |
| Dimethyl Sulfoxide SCHEMBL835357 | 0.58 | TSHR (0.65) | — | |
| SCHEMBL11318131 | 0.58 | KDM4E (0.31) | — | |
| SCHEMBL237697 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124366-B1 | METHOD OF MEASURING BIOLOGICAL LIGANDS | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4649105-A | IMMUNOLOGY, ANTIBODY AND ENZYMES, INHIBITORS | FUJIREBIO KABUSHIKI KAISHA (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0124366-A2 | Method of measuring biological ligands | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1984-11-07 | — | — | EP | disclosed |