Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428944 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL6784000 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL29586986 | 0.84 | POLB (0.58) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9081555 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8309710 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8013837 | 0.84 | POLB (0.58) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL338194 | 0.82 | TDP1 (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL6339253 | 0.82 | POLB (0.61) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL8013838 | 0.81 | POLB (0.59) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL27586077 | 0.81 | TSHR (0.55) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230891-B1 | ADHESION PROMOTORS, PROCESSES FOR THEIR SYNTHESIS AND THEIR USE IN POLYIMIDE-MINERAL OXIDE-METAL COMPOSITES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4778727-A | ADHESION PROMOTER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0230891-A2 | Adhesion promotors, processes for their synthesis and their use in polyimide-mineral oxide-metal composites | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1987-08-05 | — | — | EP | disclosed |