SCHEMBL338194

SCHEMBL338194

O=C(c1ccc(C(=O)Cl)c(C(=O)Cl)c1)c1ccc(C(=O)Cl)c(C(=O)Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 1/20 0.48
CDC25A P30304 1/20 0.45
CDC25B P30305 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SRD5A2 P31213 4/20 0.41
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440655 0.88 ALDH1A1 (0.40) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL75886 0.88 ALDH1A1 (0.40) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL6560811 0.84 KDM4E (0.52) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL9815475 0.82 KDM4E (0.50) TDP1HSD17B10KDM4EATMCYP1A2
SCHEMBL5034945 0.81 CDC25A (0.40) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL11473787 0.78 TSHR (0.53) L3MBTL1CDC25BHSD17B10KDM4ECYP1A2
SCHEMBL8306753 0.77 CDC25B (0.52) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL11704191 0.77 HSD17B10 (0.52) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL475973 0.77 KDM4E (0.60) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL11701892 0.77 KDM4E (0.55) TDP1L3MBTL1POLBCDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US claimed
EP-3649194-B1 THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED UV RESISTANCE INEOS STYROLUTION GROUP GMBH (DE) 2024-06-12 EP disclosed
US-20240182707-A1 POLYCARBONATE BLEND COMPOSITIONS HAVING IMPROVED WEATHERABILITY AND SCRATCH RESISTANCE COVESTRO LLC 2024-06-06 US disclosed
EP-4153682-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-06-05 EP disclosed
EP-4153681-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-05-29 EP disclosed
EP-4367166-A1 COMPOSITION AND METHOD FOR PRODUCING A TRANSPARENT THERMOPLASTIC POLYCARBONATE/POLYMETHYL METHACRYLATE MOULDING COMPOUND Covestro Deutschland AG (DE) 2024-05-15 EP disclosed
US-20240132661-A1 COMPOSITION AND PROCESS FOR PRODUCING A TRANSLUCENT THERMOPLASTIC POLYCARBONATE-POLYMETHYL METHACRYLATE MOLDING COMPOUND COVESTRO DEUTSCHLAND AG (DE) 2024-04-25 US disclosed
US-11965066-B2 Thermoplastic compositions with improved UV resistance INEOS STYROLUTION GROUP GMBH (DE) 2024-04-23 US disclosed
US-20240117171-A1 BLACK STYRENE COPOLYMER COMPOSITIONS FOR HIGH GLOSS EXTERIOR APPLICATIONS INEOS STYROLUTION GROUP GMBH (DE) 2024-04-11 US disclosed
WO-2024068403-A1 E/E COMPONENT CONTAINING POLYCARBONATE MATERIAL HAVING HIGH TRACKING RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2024-04-04 WO disclosed
US-4937311-A Heat resistant molding material BAYER AKTIENGESELLSCHAFT, LEVERKUSEN, GERMANY, A CORP. OF GERMANY (DE) 1990-06-26 US disclosed
US-4937285-A Use of redox graft polymers to improve the petroleum-resistance of thermoplastic, aromatic polycarbonate and/or polyester carbonate moulding compositions BAYER AKTIENGESELLSCHAFT (DE) 1990-06-26 US disclosed
US-4929674-A AND ALKYL (METH)ACRYLATE GRAFTED DIENE RUBBER BAYER AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
US-4740554-A BLEND WITH ADDITION POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1988-04-26 US disclosed
US-4719279-A POLYESTERS, POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed
US-4714746-A Process for the preparation of aromatic polyester-carbonates having improved notched impact strength, and polyester-carbonates prepared thereby and their use for the production of mouldings, films and coatings BAYER AKTIENGESELLSCHAFT (DE) 1987-12-22 US disclosed
US-4704430-A BLENDS OF POLYCARBONATES, POLYESTERS AND BLOCK POLYCARBONATE ETHER COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1987-11-03 US disclosed
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
US-4334053-A CHAIN TERMINATED BY ALKYL-SUBSTITUTED PHENOL, PHENYL HALOGORMATES OR PHENYLACYL CHLORIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed