Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224574 | 0.80 | MAPK14 (0.65) | MAPK14AKR1B1 | |
| SCHEMBL5365075 | 0.79 | PRF1 (0.68) | — | |
| SCHEMBL4220942 | 0.78 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL4220120 | 0.77 | MAPK14 (0.81) | MAPK14 | |
| SCHEMBL4219699 | 0.76 | MAPK14 (0.65) | MAPK14AKR1B1 | |
| SCHEMBL4217396 | 0.75 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4223774 | 0.75 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL4219979 | 0.74 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL29375440 | 0.74 | MAPT (0.67) | MAPK14AKR1B1 | |
| SCHEMBL86392 | 0.74 | MAPT (0.67) | MAPK14AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3133974-A | — | — | None | — | — | JP | disclosed |
| JP-H03133974-A | NEW SULFONAMIDE DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1991-06-07 | — | — | JP | disclosed |