Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815482 | 0.79 | MAPK14 (0.60) | — | |
| SCHEMBL5558567 | 0.77 | MAPT (0.61) | PRF1ALDH1A1PKMKDM4EMAPT | |
| SCHEMBL1631242 | 0.77 | PGR (0.60) | PRF1ALDH1A1PKMKDM4EGAA | |
| SCHEMBL3624124 | 0.76 | MAPT (0.55) | PRF1ALDH1A1PKMKDM4EMAPT | |
| SCHEMBL5764438 | 0.75 | MAPT (0.68) | ALDH1A1KDM4EMAPTGAAHTT | |
| SCHEMBL1091899 | 0.74 | PTGS2 (0.48) | GAAHSD17B10 | |
| SCHEMBL29606212 | 0.73 | MAPT (0.66) | ALDH1A1KDM4EMAPTGAALMNA | |
| SCHEMBL27354573 | 0.72 | ALDH1A1 (0.45) | PRF1ALDH1A1PKMKDM4EMAPT | |
| SCHEMBL18022673 | 0.72 | TDP2 (0.55) | ALDH1A1 | |
| SCHEMBL9715425 | 0.72 | BAZ2B (0.60) | ALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129169-A2 | COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL | PFIZER LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
| US-5968958-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS OR ENZYME INHIBITORS | MERCK FROSST CANADA, INC. (CA) | 1999-10-19 | — | — | US | disclosed |