Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | CALML3 | P27482 | 1/20 | 0.56 |
| ▸ | SDHA | P31040 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 8/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815509 | 0.92 | F10 (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL9815486 | 0.89 | MAOA (0.57) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL13298924 | 0.86 | MAOA (0.61) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL9550281 | 0.86 | MAOA (0.54) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL10756140 | 0.85 | MAOA (0.53) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL15367964 | 0.85 | MAOA (0.60) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL16703808 | 0.85 | MAOA (0.60) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL9550292 | 0.85 | MAOA (0.60) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL8590209 | 0.84 | MAOA (0.59) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL9823761 | 0.84 | MAOA (0.65) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127902-B1 | AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| US-4705799-A | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0127902-A2 | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-12-12 | — | — | EP | disclosed |