SCHEMBL9815560

SCHEMBL9815560

CCN(N=Cc1ccc2c(c1)c1ccccc1n2C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.48
POLB P06746 5/20 0.48
PKM P14618 2/20 0.48
HTT P42858 2/20 0.48
ALDH1A1 P00352 8/20 0.46
HPGD P15428 6/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
LMNA P02545 5/20 0.46
MAPT P10636 4/20 0.46
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46
CASP1 P29466 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SRC P12931 3/20 0.46
KMT2A Q03164 7/20 0.45
MEN1 O00255 6/20 0.45
APOBEC3A P31941 1/20 0.45
RAB9A P51151 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702588 0.89 KDM4E (0.63) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL11123338 0.88 KMT2A (0.56) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL11117842 0.87 KDM4E (0.52) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL11120868 0.87 KDM4E (0.49) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL1335846 0.84 KMT2A (0.48) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL13219228 0.84 KMT2A (0.48) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL1335849 0.84 KMT2A (0.48) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL9815537 0.83 KMT2A (0.50) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL14283649 0.81 MAPT (0.47) KDM4EPOLBPKMHTTALDH1A1
SCHEMBL14001807 0.80 KDM4E (0.60) KDM4EPOLBPKMHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4365014-A CARBAZOLE HYDRAZONE COMPOUNDS AS CHARGE TRANSPORT MATERIALS RICOH COMPANY, LIMITED (JP) 1982-12-21 US claimed
EP-0187013-B1 PHOTOCONDUCTIVE IMAGING MEMBER XEROX CORPORATION (US) 1991-10-16 EP disclosed
US-4563408-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-01-07 US disclosed
US-4454212-A PHENYLHYDRAZONE OF CARBAZOLE ALDEHYDE RICOH COMPANY LIMITED (JP) 1984-06-12 US disclosed
EP-0013172-B1 ELECTROPHOTOGRAPHIC ELEMENTS Ricoh Company, Ltd (JP) 1983-09-07 EP disclosed
EP-0013172-A2 Electrophotographic elements Ricoh Company, Ltd (JP) 1980-07-09 EP disclosed