SCHEMBL9815537

SCHEMBL9815537

CN(N=Cc1ccc2c(c1)c1ccccc1n2C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.50
MEN1 O00255 8/20 0.50
MAPT P10636 6/20 0.50
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HPGD P15428 2/20 0.50
LMNA P02545 2/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
POLB P06746 6/20 0.47
TDP1 Q9NUW8 2/20 0.47
APOBEC3A P31941 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
ALOX12 P18054 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 3/20 0.45
HTT P42858 2/20 0.45
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16900542 0.90 POLB (0.56) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL13219228 0.88 KMT2A (0.48) KMT2AMEN1MAPTRAB9ASMN1; SMN2
SCHEMBL1335846 0.88 KMT2A (0.48) KMT2AMEN1MAPTRAB9ASMN1; SMN2
SCHEMBL1335849 0.88 KMT2A (0.48) KMT2AMEN1MAPTRAB9ASMN1; SMN2
SCHEMBL14224628 0.87 KDM4E (0.52) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL29438474 0.86 KDM4E (0.64) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL128424 0.86 KDM4E (0.64) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL1596345 0.86 KDM4E (0.64) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL14196868 0.86 KMT2A (0.43) KMT2AMEN1MAPTRAB9ANPC1
SCHEMBL9815560 0.83 KDM4E (0.48) KMT2AMEN1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4365014-A CARBAZOLE HYDRAZONE COMPOUNDS AS CHARGE TRANSPORT MATERIALS RICOH COMPANY, LIMITED (JP) 1982-12-21 US claimed
US-7848694-B2 Image forming device, processing unit, and image forming method RICOH COMPANY, LTD. (JP) 2010-12-07 US disclosed
EP-0187013-B1 PHOTOCONDUCTIVE IMAGING MEMBER XEROX CORPORATION (US) 1991-10-16 EP disclosed
EP-0187013-A2 Photoconductive imaging member XEROX CORPORATION (US) 1986-07-09 EP disclosed
US-4563408-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-01-07 US disclosed
US-4454212-A PHENYLHYDRAZONE OF CARBAZOLE ALDEHYDE RICOH COMPANY LIMITED (JP) 1984-06-12 US disclosed
EP-0013172-B1 ELECTROPHOTOGRAPHIC ELEMENTS Ricoh Company, Ltd (JP) 1983-09-07 EP disclosed
US-4365014-A CARBAZOLE HYDRAZONE COMPOUNDS AS CHARGE TRANSPORT MATERIALS RICOH COMPANY, LIMITED (JP) 1982-12-21 US disclosed
EP-0013172-A2 Electrophotographic elements Ricoh Company, Ltd (JP) 1980-07-09 EP disclosed