Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815793 | 0.92 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL9815814 | 0.85 | ABCB1 (0.65) | ABCB1 | |
| SCHEMBL9714259 | 0.83 | ABCB1 (0.69) | ABCB1 | |
| SCHEMBL9815811 | 0.83 | ABCB1 (0.65) | ABCB1 | |
| SCHEMBL9425386 | 0.83 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL9815834 | 0.83 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL9426147 | 0.82 | POLB (0.56) | ABCB1 | |
| SCHEMBL9425963 | 0.81 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL8173402 | 0.81 | MEN1 (0.55) | ABCB1 | |
| SCHEMBL9425270 | 0.81 | ABCB1 (0.64) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |