Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166298 | 0.91 | POLB (0.68) | POLBMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL9815800 | 0.90 | POLB (0.56) | POLBMEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL9425270 | 0.89 | ABCB1 (0.64) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL8173935 | 0.89 | POLB (0.55) | POLBMEN1KMT2APTGS2CYP3A4 | |
| SCHEMBL9425963 | 0.86 | ABCB1 (0.64) | POLBMEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL9815842 | 0.86 | HPGD (0.68) | POLBABCB1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL8173402 | 0.84 | MEN1 (0.55) | POLBMEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL9815808 | 0.83 | TLR7 (0.64) | POLBMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL9815796 | 0.82 | ABCB1 (0.64) | ABCB1 | |
| SCHEMBL9815864 | 0.81 | ABCB1 (0.60) | POLBABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |