Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29370733 | 1.00 | LTA4H (0.53) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| Ammonia Solution, Strong SCHEMBL29399251 | 1.00 | LTA4H (0.53) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29355173 | 0.99 | LTA4H (0.54) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL1870730 | 0.99 | LTA4H (0.54) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL14586345 | 0.99 | LTA4H (0.54) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29193905 | 0.87 | LTA4H (0.43) | LTA4HMEN1KMT2AGRM8GRM4 | |
| Ammonia Solution, Strong SCHEMBL30421194 | 0.84 | LTA4H (0.46) | LTA4HALDH1A1LMNA | |
| SCHEMBL9816016 | 0.84 | LTA4H (0.53) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL8378243 | 0.82 | LTA4H (0.46) | LTA4HALDH1A1LMNA | |
| SCHEMBL31458519 | 0.82 | LTA4H (0.46) | LTA4HALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297607-B1 | GAMMA-L-GLUTAMYL-4-NITROANILIDE DERIVATIVES AND PROCESS FOR DETERMINING GAMMA-GTP ACTIVITY USING THE SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4851572-A | DIAGNOSIS OF LIVER AND BILE DUCT DISORDERS, ALCOHOLISM | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0297607-A1 | Gamma-L-glutamyl-4-nitroanilide derivatives and process for determining gamma-GTP activity using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |