Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230938 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL2948875 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL6627461 | 1.00 | — | — | |
| SCHEMBL7530097 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL21495046 | 0.97 | — | — | |
| SCHEMBL918055 | 0.97 | — | — | |
| Ethylene SCHEMBL7388735 | 0.95 | KMT2A (0.48) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL2342739 | 0.89 | — | — | |
| SCHEMBL13125935 | 0.75 | KMT2A (0.46) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL1551749 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861917-A | Process for preparing macrocyclic 2-halogenoketones | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-08-29 | — | — | US | claimed |
| WO-2025035202-A1 | IONIZABLE LIPIDS COMPRISING MACROCYCLIC RINGS FOR THE DELIVERY OF THERAPEUTIC AGENTS | NANOVATION THERAPEUTICS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| EP-0290015-B1 | PROCESS FOR PREPARING MACROCYCLIC 2-HALOGENOKETONES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4861917-A | Process for preparing macrocyclic 2-halogenoketones | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0290015-A1 | Process for preparing macrocyclic 2-Halogenoketones | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-11-09 | — | — | EP | disclosed |