SCHEMBL9816360

SCHEMBL9816360

CCNC(=S)Nc1c(C)cc(C)c(C2CC(=O)C(C(=O)CC)=C(O)C2)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10680604 0.86 RAB9A (0.34) RAB9A
SCHEMBL9816358 0.85 RAB9A (0.34) RAB9A
SCHEMBL9816318 0.85 RAB9A (0.37) ALDH1A1RAB9A
SCHEMBL9816310 0.83 RAB9A (0.32) RAB9A
SCHEMBL9816297 0.81 RAB9A (0.33) RAB9A
SCHEMBL10703633 0.78 RAB9A (0.34) RAB9A
SCHEMBL10503664 0.77 RAB9A (0.37) ALDH1A1RAB9A
SCHEMBL9816420 0.77 RAB9A (0.37) ALDH1A1RAB9A
SCHEMBL9816300 0.76 RAB9A (0.36) ALDH1A1RAB9A
SCHEMBL9807016 0.76 RAB9A (0.33) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209283-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1991-10-16 EP disclosed
US-4888043-A FOR MONOCOTYLEDONOUS WEEDS IN DICOTYLEDONOUS CROPS; 2-OXIMIDO-4-(2,4,6-TRIMETHYL-3-AMINO-SUBSTITUENT-PHENYL)CYCLO-HEX-1-ENE-1,3 -DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1989-12-19 US disclosed
EP-0209283-A2 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-01-21 EP disclosed