Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CPN1 | P15169 | 5/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572076 | 0.82 | ALDH1A1 (0.44) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL27334906 | 0.79 | CYP2C9 (0.43) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL27542152 | 0.79 | EPHX1 (0.44) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL439640 | 0.78 | SMN1; SMN2 (0.49) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL24934006 | 0.77 | KMT2A (0.45) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27751845 | 0.77 | SMN1; SMN2 (0.47) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL4978863 | 0.76 | SMN1; SMN2 (0.46) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL435610 | 0.75 | CYP2C9 (0.45) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL2403226 | 0.75 | ALDH1A1 (0.46) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 | |
| SCHEMBL10837481 | 0.75 | CYP2C9 (0.42) | CYP2C9CYP2C19HIF1AEPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174271-B1 | ANTHRACEME DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0174271-A2 | Anthraceme derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |