Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816444 | 0.94 | CA2 (0.52) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL10882144 | 0.93 | GRIK1 (0.53) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL9816450 | 0.93 | GRIK1 (0.53) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL9816519 | 0.93 | GRIK1 (0.53) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL9816520 | 0.88 | CHRM1 (0.67) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL31756901 | 0.88 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28466870 | 0.84 | CA2 (0.63) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| Acetic Acid SCHEMBL7601152 | 0.83 | CA2 (0.74) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| Acetic Acid SCHEMBL727880 | 0.83 | CA2 (0.74) | CA2MAPK1SLC1A2SLC1A1CHRM1 | |
| SCHEMBL593706 | 0.83 | CA2 (0.81) | CA2MAPK1SLC1A2SLC1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174271-B1 | ANTHRACEME DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0174271-A2 | Anthraceme derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |