Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726590 | 0.94 | KDM4E (0.52) | KMT2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7947086 | 0.90 | KMT2A (0.51) | KMT2AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL15100552 | 0.86 | NPC1 (0.46) | KMT2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1558506 | 0.85 | KDM4E (0.53) | KMT2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29387256 | 0.83 | CYP3A4 (0.55) | KMT2AALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL333141 | 0.83 | CYP3A4 (0.55) | KMT2AALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL10669335 | 0.81 | CYP3A4 (0.59) | KMT2AALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL9177911 | 0.81 | KCNK3 (0.56) | KMT2AHSD17B10NPC1RAB9AKCNK3 | |
| SCHEMBL18739643 | 0.80 | HSD17B10 (0.55) | KMT2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL305252 | 0.80 | ALDH1A1 (0.70) | KMT2AKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135714-B1 | SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS | MELAMINE CHEMICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |