Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816744 | 0.81 | ANPEP (0.38) | GNAI3GNAO1GNAI1DNM1ALDH1A1 | |
| SCHEMBL9816831 | 0.79 | KDM4E (0.35) | ADRB2 | |
| SCHEMBL9576901 | 0.77 | PLA2G1B (0.44) | SPHK1PLA2G1BPLA2G2ALMNA | |
| SCHEMBL29234718 | 0.75 | PLA2G1B (0.44) | SPHK1PLA2G1BPLA2G2ADNM1ALDH1A1 | |
| SCHEMBL7092733 | 0.75 | PLA2G1B (0.44) | SPHK1PLA2G1BPLA2G2ADNM1ALDH1A1 | |
| SCHEMBL25356241 | 0.75 | DNM1 (0.45) | SPHK1PLA2G1BPLA2G2AGNAI3GNAO1 | |
| SCHEMBL7095679 | 0.75 | PLA2G1B (0.44) | SPHK1PLA2G1BPLA2G2ADNM1ALDH1A1 | |
| SCHEMBL9337939 | 0.75 | TRPV1 (0.40) | ADRB2SPHK1GNAI3GNAO1GNAI1 | |
| SCHEMBL8382119 | 0.75 | KDM4E (0.42) | PLA2G1BPLA2G2ADNM1ALDH1A1MEN1 | |
| SCHEMBL14833428 | 0.74 | PLA2G1B (0.44) | SPHK1PLA2G1BPLA2G2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273342-B1 | 1,3-BIS-SUBSTITUTED-2-PROPANOL DERIVATIVES CONTAINING AMINO GROUPS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-4885392-A | Derivatives of 1,3-bissubstituted 2-propanol containing amino groups, methods for their preparation and their use | HOECHST AG (DE) | 1989-12-05 | — | — | US | disclosed |
| EP-0273342-A1 | 1,3-Bis-substituted-2-propanol derivatives containing amino groups, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-06 | — | — | EP | disclosed |