SCHEMBL9816871

SCHEMBL9816871

CCCCCCC(C)OC(=O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
CTRC Q99895 1/20 0.52
TSHR P16473 1/20 0.49
RARB P10826 3/20 0.49
MAOB P27338 1/20 0.49
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
PARP10 Q53GL7 1/20 0.46
ACACB O00763 1/20 0.46
MMP12 P39900 1/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SRD5A2 P31213 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799716 0.97 ALDH1A1 (0.57) ALDH1A1CTRCTSHRMAOBNR4A1
SCHEMBL9346509 0.97 ALDH1A1 (0.57) ALDH1A1CTRCTSHRMAOBNR4A1
SCHEMBL9504781 0.91 RARB (0.55) ALDH1A1TSHRRARBLMNARXRA
SCHEMBL8609008 0.89 RARB (0.55) TSHRRARBLMNARXRARXRB
SCHEMBL16602456 0.87 TSHR (0.58) ALDH1A1TSHRRARBLMNARXRA
SCHEMBL9779542 0.87 ALDH1A1 (0.52) ALDH1A1CTRCMAOBNR4A1NR4A2
SCHEMBL9799530 0.87 ALDH1A1 (0.52) ALDH1A1CTRCMAOBNR4A1NR4A2
SCHEMBL9799527 0.87 ALDH1A1 (0.52) ALDH1A1CTRCMAOBNR4A1NR4A2
SCHEMBL9437156 0.86 MAOB (0.56) ALDH1A1MAOBNR4A1NR4A2NR4A3
SCHEMBL9502531 0.86 RARB (0.63) ALDH1A1TSHRRARBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0216530-B1 LIQUID CRYSTAL CARBONATOBENZOIC ACID DERIVATIVE AND COMPOSITION Chisso Corporation (JP) 1991-10-23 EP disclosed
US-4816181-A FOR DISPLAYS CHISSO CORPORATION (JP) 1989-03-28 US disclosed
EP-0216530-A1 Liquid crystal carbonatobenzoic acid derivative and composition Chisso Corporation (JP) 1987-04-01 EP disclosed