SCHEMBL9816883

SCHEMBL9816883

CCN(Cc1ccccc1)C(C)CO

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.51
TSHR P16473 6/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 1/20 0.47
NPBWR1 P48145 1/20 0.47
MCHR1 Q99705 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
ADRA2B P18089 3/20 0.46
HTR2A P28223 3/20 0.46
KCNH2 Q12809 3/20 0.46
ADRA2C P18825 2/20 0.46
SLC6A2 P23975 2/20 0.46
ADRA1A P35348 2/20 0.46
SLC6A3 Q01959 2/20 0.46
SLC6A4 P31645 1/20 0.46
OPRK1 P41145 1/20 0.46
LMNA P02545 2/20 0.44
TRPA1 O75762 1/20 0.44
ADRA2A P08913 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816880 1.00 BCHE (0.51) BCHETSHRKMT2ANPSR1GAA
SCHEMBL6054336 0.90 TSHR (0.51) BCHETSHRKMT2ANPSR1GAA
SCHEMBL1834929 0.90 TSHR (0.51) BCHETSHRKMT2ANPSR1GAA
SCHEMBL1834931 0.90 TSHR (0.51) BCHETSHRKMT2ANPSR1GAA
SCHEMBL20012414 0.86 BCHE (0.56) BCHETSHRKMT2ANPSR1GAA
SCHEMBL19472433 0.85 BCHE (0.51) BCHETSHRKMT2ANPSR1SIGMAR1
SCHEMBL12126080 0.85 BCHE (0.54) BCHETSHRKMT2ANPSR1SIGMAR1
SCHEMBL13048982 0.84 BCHE (0.40) BCHENPSR1SLC6A2SLC6A4OPRK1
SCHEMBL3931095 0.84 SIGMAR1 (0.53) BCHETSHRKMT2ANPSR1GAA
SCHEMBL9841066 0.82 CYP2C19 (0.49) TSHRKMT2ANPSR1GAANPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301925-B1 PROCESS FOR THE ENANTIOSPECIFIC PREPARATION OF (S)2-ETHYL AMINO-1-3-(TRIFLUOROMETHYL PHENYL) PROPANE ADIR ET COMPAGNIE (FR) 1991-10-23 EP claimed
EP-3858349-A1 NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME Japan Tobacco Inc. (JP) 2021-08-04 EP disclosed
EP-3442965-B1 NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES BOEHRINGER INGELHEIM INT (DE) 2021-05-26 EP disclosed
EP-3442967-B1 NOVEL N-[(PYRIMIDINYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2020-05-13 EP disclosed
EP-3442958-B1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2020-05-06 EP disclosed
EP-3442963-B1 N-[(PYRAZINYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2020-05-06 EP disclosed
WO-2017178339-A1 NOVEL N-[(PYRAZINYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-10-19 WO disclosed
WO-2017178344-A1 NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-10-19 WO disclosed
WO-2017178338-A1 NOVEL N-[(PYRIMIDINYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-10-19 WO disclosed
WO-2017178340-A1 NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2017-10-19 WO disclosed