SCHEMBL9817065

SCHEMBL9817065

CCCCCC(c1ccc(C)cc1)(c1ccc(O)c(-c2ccccc2)c1)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.50
CNR1 P21554 15/20 0.44
CNR2 P34972 15/20 0.44
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817052 0.96 KIF11 (0.51) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9817028 0.93 KIF11 (0.44) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9817109 0.91 KIF11 (0.47) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9816991 0.89 ESR1 (0.45) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9817002 0.87 CNR1 (0.44) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9713821 0.86 CNR1 (0.50) KIF11CNR1CNR2KCNH2
SCHEMBL9713278 0.86 CNR1 (0.45) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9816982 0.85 CNR1 (0.42) KIF11CNR1CNR2ESR1KCNH2
SCHEMBL9816990 0.85 KIF11 (0.43) KIF11CNR1CNR2ESR1ESR2
SCHEMBL9817058 0.85 CNR1 (0.44) CNR1CNR2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed