SCHEMBL9817121

SCHEMBL9817121

COc1ccc(/N=N/c2c(C)c(C#N)c(=O)n(C)c2O)cc1S(=O)(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 14/20 0.51
▸ KMT2A Q03164 11/20 0.51
▸ MEN1 O00255 10/20 0.51
▸ ALDH1A1 P00352 5/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ PKM P14618 1/20 0.43
▸ KDM4E B2RXH2 8/20 0.42
▸ LMNA P02545 3/20 0.42
▸ HTT P42858 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ MITF O75030 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ GAA P10253 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ PTGS1 P23219 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ MCL1 Q07820 1/20 0.35
▸ HPGD P15428 1/20 0.34
▸ MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817126 1.00 MAPT (0.51) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11107320 0.81 KMT2A (0.40) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11107326 0.81 KMT2A (0.40) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL8972947 0.79 KMT2A (0.56) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL18335256 0.78 MAPT (0.54) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL18335257 0.78 MAPT (0.54) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10184550 0.75 MAPT (0.65) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11058973 0.73 KMT2A (0.56) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11058970 0.73 KMT2A (0.56) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10119039 0.73 KMT2A (0.53) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0066282-B2 HEAT-DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1991-09-25 — — EP disclosed
EP-0066282-B1 HEAT-DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1986-01-02 — — EP disclosed
US-4478927-A SILVER HALIDE EMULSION, ORGANIC SILVER SALT, BINDER, AND DYE-RELEASING REDOX COMPOUND; PHOTOTHERMOGRAPHY; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 — — US disclosed
EP-0066282-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-08 — — EP disclosed
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