SCHEMBL9817136

SCHEMBL9817136

CC(C)(C)OOC(C)(C)C.CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-].[Ti+4]

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutane SCHEMBL28312130 0.81 TSHR (0.73) TSHRTDP1
Tert-Butyl Hydroperoxide SCHEMBL9817088 0.79
Tert-Butyl Hydroperoxide SCHEMBL9817089 0.76 ALDH1A1 (0.60)
SCHEMBL28236221 0.76 TDP1 (1.00) TSHRTDP1
SCHEMBL14861 0.76 TDP1 (1.00) TSHRTDP1
Isopropyl Alcohol SCHEMBL28991490 0.74 TSHR (0.61) TSHRTDP1
Isobutyraldehyde SCHEMBL27744722 0.73 TDP1 (0.50) TSHRTDP1
Hydrochloric Acid SCHEMBL25381110 0.71 TSHR (0.89) TSHRTDP1
SCHEMBL7526385 0.71 TSHR (0.89) TSHRTDP1
SCHEMBL10413085 0.71 TSHR (0.89) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190042-B1 ORGANIC COMPOUNDS AND THEIR PHARMACEUTICAL USE Lilly Industries Limited (GB) 1991-10-30 EP disclosed
EP-0201823-B1 NOVEL INTERMEDIATES FOR THE PRODUCTION OF PHARMACEUTICALS LILLY INDUSTRIES LIMITED (GB) 1990-12-05 EP disclosed
US-4963578-A LEUKOTRIN ANTAGONISTS; ANTIALLERGENS LILLY INDUSTRIES LIMITED (GB) 1990-10-16 US disclosed
EP-0186426-B1 TETRAZOLYL COMPOUNDS AND THEIR PHARMACEUTICAL USE Lilly Industries Limited (GB) 1990-09-12 EP disclosed
US-RE33300-E LEUKOTRIENE ANTAGONISTS; ANTIALLERGENS ELI LILLY AND COMPANY (US) 1990-08-14 US disclosed
EP-0134111-B1 ARALIPHATIC SULPHIDES,SULPHONES AND SULPHOXIDES AND THEIR PHARMACEUTICAL USE Lilly Industries Limited (GB) 1988-12-07 EP disclosed
US-4665189-A LEUKOTRIENE ANTAGONISTS LILLY INDUSTRIES LIMITED (GB) 1987-05-12 US disclosed
EP-0201823-A2 Novel intermediates for the production of pharmaceuticals LILLY INDUSTRIES LIMITED (GB) 1986-11-20 EP disclosed
EP-0190042-A2 Organic compounds and their pharmaceutical use Lilly Industries Limited (GB) 1986-08-06 EP disclosed
EP-0186426-A2 Tetrazolyl compounds and their pharmaceutical use Lilly Industries Limited (GB) 1986-07-02 EP disclosed
EP-0134111-A1 Araliphatic sulphides,sulphones and sulphoxides and their pharmaceutical use Lilly Industries Limited (GB) 1985-03-13 EP disclosed