Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 8/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817184 | 1.00 | LMNA (0.48) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5016930 | 0.83 | LMNA (0.58) | LMNAHDAC11CES2CES1ALDH1A1 | |
| SCHEMBL28723570 | 0.83 | LMNA (0.58) | LMNAHDAC11KDM5AKDM4CPHF8 | |
| SCHEMBL28987987 | 0.83 | LMNA (0.58) | LMNAHDAC11CES2CES1ALDH1A1 | |
| SCHEMBL17501644 | 0.83 | LMNA (0.58) | LMNAHDAC11KDM5AKDM4CPHF8 | |
| SCHEMBL12640149 | 0.83 | LMNA (0.58) | LMNAHDAC11CES2CES1ALDH1A1 | |
| SCHEMBL9657056 | 0.83 | LMNA (0.58) | LMNAHDAC11KDM5AKDM4CPHF8 | |
| SCHEMBL28581774 | 0.83 | LMNA (0.58) | LMNAHDAC11KDM5AKDM4CPHF8 | |
| SCHEMBL12924011 | 0.83 | LMNA (0.58) | LMNAHDAC11CES2CES1ALDH1A1 | |
| SCHEMBL728435 | 0.83 | LMNA (0.58) | LMNAHDAC11KDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269940-B1 | SURFACE ACTIVE AGENT AND PROCESS FOR PREPARING THE SAME | Kao Corporation (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-4885112-A | CONTAINING LOW PERCENTAGE OF INORGANIC SALT; COMPATIBILITY, STABILITY | KAO CORPORATION (JP) | 1989-12-05 | — | — | US | disclosed |