SCHEMBL9817243

SCHEMBL9817243

Cc1nc(N)c(CN)c(Cl)n1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
DPP4 P27487 15/20 0.37
MBOAT4 Q96T53 2/20 0.35
CYP3A4 P08684 1/20 0.32
DPP8 Q6V1X1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259365 0.83 SMN1; SMN2 (0.42) HTTSMN1; SMN2MBOAT4
SCHEMBL30738986 0.79 PDK2 (0.41) HTTSMN1; SMN2MBOAT4
SCHEMBL259072 0.72 PDE10A (0.52) HTTSMN1; SMN2
SCHEMBL14165804 0.72 HTT (0.35) HTTSMN1; SMN2
SCHEMBL116212 0.72 HTT (0.37) HTTSMN1; SMN2
SCHEMBL29484711 0.72 HTT (0.35) HTTSMN1; SMN2
SCHEMBL28694432 0.70 MBOAT4 (0.34) HTTSMN1; SMN2MBOAT4
SCHEMBL31484438 0.70 KMT2A (0.44) HTTSMN1; SMN2
SCHEMBL5844067 0.69 PDK2 (0.37)
SCHEMBL7087209 0.68 PDE10A (0.35) HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3140159-A None JP disclosed
JP-H03140159-A INDICATOR COMPOSITION FOR DETECTING FORMALIN STERILIZATION NICHIYU GIKEN KOGYO KK 1991-06-14 JP disclosed