Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817590 | 1.00 | TP53 (0.54) | TP53L3MBTL1SLC18A3POLBPKM | |
| SCHEMBL9817586 | 1.00 | TP53 (0.54) | TP53L3MBTL1SLC18A3POLBPKM | |
| SCHEMBL6762506 | 0.77 | TP53 (0.62) | TP53L3MBTL1TSHRCYP19A1 | |
| SCHEMBL16179411 | 0.77 | TP53 (0.62) | TP53L3MBTL1TSHRCYP19A1 | |
| SCHEMBL4136122 | 0.74 | TP53 (0.52) | TP53L3MBTL1POLBTSHRKDM4E | |
| SCHEMBL21558172 | 0.73 | TP53 (0.54) | TP53L3MBTL1TSHR | |
| SCHEMBL27173480 | 0.73 | TP53 (0.54) | TP53L3MBTL1TSHR | |
| SCHEMBL7274841 | 0.71 | FABP5 (0.57) | SLC18A3KDM4EFABP7FABP5 | |
| SCHEMBL4059047 | 0.71 | TP53 (0.49) | TP53L3MBTL1POLBTSHRKDM4E | |
| SCHEMBL10266701 | 0.70 | TP53 (0.47) | TP53L3MBTL1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457559-A2 | Chiral synthesis of 1-aryl-3-aminopropan-1-ols | ELI LILLY AND COMPANY (US) | 1991-11-21 | — | — | EP | disclosed |