Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27822330 | 1.00 | POLB (0.47) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL9817630 | 1.00 | POLB (0.47) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL27880530 | 1.00 | POLB (0.47) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL28230232 | 1.00 | POLB (0.47) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL9312471 | 0.98 | POLB (0.44) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL9312475 | 0.98 | POLB (0.44) | POLBPOLA1CES2CES1HSP90AA1 | |
| SCHEMBL27309128 | 0.92 | CES1 (0.41) | POLBPOLA1CES2CES1TSHR | |
| SCHEMBL28200375 | 0.92 | FAAH (0.54) | POLBPPARGPPARDPPARAPTPN1 | |
| Ethylene Glycol SCHEMBL28217841 | 0.87 | CES1 (0.37) | POLBPOLA1CES2CES1ALDH1A1 | |
| SCHEMBL29117572 | 0.86 | POLB (0.49) | POLBPOLA1CES2CES1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055221-A | Rapidly switching ferroelectric display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |
| US-4820839-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-11 | — | — | US | disclosed |