Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecylamine SCHEMBL11149028 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL29883666 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL29111186 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Dodecylamine SCHEMBL9551516 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL11504036 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL25341518 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9614783 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Tetradecylamine SCHEMBL8731499 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL9444046 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL27576695 | 1.00 | DNM1 (0.62) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241278-B1 | METHOD OF SEPARATING AND PURIFYING TANTALUM AND NIOBIUM-CONTAINING COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | claimed |
| CN-104603303-A | Processes for recovering rare earth elements and rare metals | ORBITE ALUMINAE INC | 2015-05-06 | — | — | CN | disclosed |
| US-4370402-A | Dye reducing composition for dye transfers, photographic transparencies and color prints | ANDERSON HARRY | 1983-01-25 | — | — | US | disclosed |