SCHEMBL9818110

SCHEMBL9818110

Cc1cccc(C=CC(=O)O)c1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
NFKB1 P19838 1/20 0.53
CA4 P22748 1/20 0.53
PTGER3 P43115 7/20 0.52
PTGER2 P43116 7/20 0.52
PTGER4 P35408 5/20 0.52
PTGER1 P34995 4/20 0.52
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
HDAC3 O15379 1/20 0.46
TNKS O95271 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818109 1.00 CA1 (0.53) CA1CA2NFKB1CA4PTGER3
SCHEMBL78555 0.83 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL78556 0.83 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL29386378 0.83 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL2425317 0.83 CA1 (0.62) CA1CA2NFKB1CA4PTGER3
SCHEMBL17802338 0.83 CA1 (0.53) CA1CA2NFKB1CA4PTGER3
Ammonia Solution, Strong SCHEMBL6324720 0.82 CA1 (0.60) CA1CA2NFKB1CA4PTGER3
Hydrochloric Acid SCHEMBL9445634 0.82 CA1 (0.60) CA1CA2NFKB1CA4PTGER3
SCHEMBL5666241 0.82 CA1 (0.60) CA1CA2NFKB1CA4PTGER3
Ammonia Solution, Strong SCHEMBL6324726 0.82 CA1 (0.60) CA1CA2NFKB1CA4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4762948-A USING METALLOCENYL PHOSPHINE REDUCING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-09 US claimed
EP-0275354-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE ARYLACETIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-16 EP disclosed
US-4762948-A USING METALLOCENYL PHOSPHINE REDUCING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-09 US disclosed
EP-0275354-A1 Process for preparing optically active arylacetic acid derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-27 EP disclosed