Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635920 | 0.84 | HTR2C (0.43) | HTR2AHTR2BHTR2CTSHRMEN1 | |
| SCHEMBL9668305 | 0.78 | TSHR (0.34) | TSHR | |
| SCHEMBL28642739 | 0.75 | HTR2B (0.37) | HTR2AHTR2BHTR2CSMN1; SMN2HTT | |
| SCHEMBL9635848 | 0.75 | AR (0.37) | HTR2AHTR2BHTR2CNPSR1TSHR | |
| SCHEMBL23997598 | 0.74 | CYP3A4 (0.32) | SMN1; SMN2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL11302784 | 0.74 | HTR2B (0.55) | HTR2AHTR2BHTR2CSMN1; SMN2NPSR1 | |
| SCHEMBL10798707 | 0.71 | TSHR (0.42) | TSHRCHRM4CHRM1SLC6A2SLC6A4 | |
| SCHEMBL28631496 | 0.70 | CYP2C9 (0.41) | HTR2BSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL11098842 | 0.69 | HTR2B (0.54) | HTR2AHTR2BHTR2CSMN1; SMN2NPSR1 | |
| SCHEMBL2945319 | 0.68 | HTR1A (0.36) | HTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246002-B1 | ALKENAMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-27 | — | — | EP | disclosed |