SCHEMBL9818165

SCHEMBL9818165

C=CCC(CC)(SC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9111003 0.80 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL9567347 0.76 GGPS1 (0.32)
SCHEMBL11498755 0.71 ALDH1A1 (0.37) ALDH1A1TSHRHTT
SCHEMBL7252450 0.70 ALDH1A1 (0.39) ALDH1A1TSHRHTT
SCHEMBL1716936 0.70 ALDH1A1 (0.39) ALDH1A1TSHRHTT
SCHEMBL11131461 0.70 ALDH1A1 (0.39) ALDH1A1TSHRHTT
SCHEMBL5703515 0.68 ALDH1A1 (0.38) ALDH1A1TSHRHTT
SCHEMBL1717016 0.68 TSHR (0.41) ALDH1A1TSHRHTT
SCHEMBL1378857 0.67 ALDH1A1 (0.37) ALDH1A1TSHRHTT
SCHEMBL5904292 0.67 ALDH1A1 (0.50) ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330254-B1 ALKYL (3-METHYLTHIO)-BUTYRATES, AS WELL AS FLAVOUR COMPOSITIONS AND FLAVOURED FOODSTUFFS AND STIMULANTS CONTAINING ONE OR MORE OF THESE COMPOUNDS AS FLAVOUR COMPONENT NAARDEN INTERNATIONAL N.V. (NL) 1991-11-27 EP claimed
EP-0330254-B1 ALKYL (3-METHYLTHIO)-BUTYRATES, AS WELL AS FLAVOUR COMPOSITIONS AND FLAVOURED FOODSTUFFS AND STIMULANTS CONTAINING ONE OR MORE OF THESE COMPOUNDS AS FLAVOUR COMPONENT NAARDEN INTERNATIONAL N.V. (NL) 1991-11-27 EP disclosed
EP-0330254-A1 Alkyl (3-methylthio)-butyrates, as well as flavour compositions and flavoured foodstuffs and stimulants containing one or more of these compounds as flavour component NAARDEN INTERNATIONAL N.V. (NL) 1989-08-30 EP disclosed