Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19598395 | 0.79 | PDGFRB (0.36) | PDGFRBPDGFRALRRK2LOXLOXL2 | |
| SCHEMBL11389109 | 0.79 | PDGFRB (0.36) | PDGFRBPDGFRALRRK2LOXLOXL2 | |
| SCHEMBL4784301 | 0.79 | PDGFRB (0.36) | PDGFRBPDGFRALRRK2LOXLOXL2 | |
| SCHEMBL10444786 | 0.79 | JAK3 (0.39) | JAK3PDGFRBPDGFRAS1PR1LRRK2 | |
| SCHEMBL9818488 | 0.71 | — | — | |
| SCHEMBL24441014 | 0.70 | PDGFRB (0.40) | KMOPDGFRBPDGFRAKMT2APDE4B | |
| Cyclohexylamine SCHEMBL295002 | 0.69 | KMT2A (0.38) | KMT2AMEN1 | |
| SCHEMBL8568954 | 0.69 | — | — | |
| SCHEMBL22895345 | 0.69 | LOX (0.47) | KMOPDGFRBPDGFRAS1PR1LRRK2 | |
| SCHEMBL12949422 | 0.69 | CDK4 (0.43) | JAK3PDGFRBPDGFRALRRK2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0144776-A2 | Fibre-reactive chromium complexes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |