Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19598395 | 0.96 | PDGFRB (0.36) | PDGFRBPDGFRAPDE4ALOXLOXL2 | |
| SCHEMBL11389109 | 0.96 | PDGFRB (0.36) | PDGFRBPDGFRAPDE4ALOXLOXL2 | |
| SCHEMBL22576502 | 0.89 | ALDH1A1 (0.40) | ALDH1A1ALOX15TSHR | |
| SCHEMBL15029308 | 0.79 | SYK (0.34) | ALDH1A1ALOX15TSHRLRRK2 | |
| SCHEMBL9818545 | 0.79 | JAK3 (0.39) | PDGFRBPDGFRALOXLOXL2MCHR1 | |
| SCHEMBL9818488 | 0.79 | — | — | |
| SCHEMBL4812179 | 0.77 | MEN1 (0.45) | ALDH1A1 | |
| SCHEMBL9309427 | 0.75 | PDGFRB (0.41) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL9862260 | 0.74 | PDGFRB (0.36) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL1402181 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718655-B2 | Trisubstituted triazine compounds, and methods for making and using the compounds, which have antitubulin activity | NEW YORK UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| US-4086204-A | LIGHT STABILIZERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-04-25 | — | — | US | disclosed |