Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006882 | 0.85 | PLAU (0.46) | PLAUALDH1A1CTSDMEN1KMT2A | |
| SCHEMBL27311079 | 0.81 | PLAU (0.42) | PLAUALDH1A1CTSDMEN1KMT2A | |
| SCHEMBL28424914 | 0.79 | HSD17B10 (0.51) | NPC1RAB9APLAUSMN1; SMN2ALDH1A1 | |
| SCHEMBL6606178 | 0.78 | PDE10A (0.46) | NPC1RAB9ATP53PDE10ASMN1; SMN2 | |
| SCHEMBL7261915 | 0.78 | PLAU (0.45) | PLAUALDH1A1CTSDMEN1KMT2A | |
| SCHEMBL10458605 | 0.77 | KMT2A (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8669115 | 0.76 | PLAU (0.46) | NPC1RAB9APLAUALDH1A1CTSD | |
| SCHEMBL6792417 | 0.75 | PLAU (0.38) | PLAUALDH1A1CTSDMEN1KMT2A | |
| SCHEMBL27479698 | 0.74 | MEN1 (0.39) | NPC1RAB9APLAUSMN1; SMN2ALDH1A1 | |
| SCHEMBL27579567 | 0.74 | PLAU (0.45) | PLAUALDH1A1CTSDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4999046-A | Herbicides and plant growth regulators, agricultural use | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4904778-A | Pyrimidine-2-phenylamino derivatives | CIBA-GEIGY CORP. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4802909-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |