Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034389 | 0.84 | CTSD (0.44) | PLAUCTSDALDH1A1GPR35KDM4E | |
| SCHEMBL29006882 | 0.82 | PLAU (0.46) | PLAUCTSDALDH1A1GPR35TDP1 | |
| SCHEMBL27490350 | 0.81 | CTSD (0.53) | PLAUCTSDALDH1A1GPR35KDM4E | |
| SCHEMBL27579567 | 0.81 | PLAU (0.45) | PLAUCTSDALDH1A1GPR35TDP1 | |
| SCHEMBL6048773 | 0.81 | ALDH1A1 (0.50) | PLAUCTSDALDH1A1GPR35TDP1 | |
| SCHEMBL30704256 | 0.81 | ALDH1A1 (0.50) | PLAUCTSDALDH1A1GPR35TDP1 | |
| SCHEMBL9631333 | 0.80 | ALDH1A1 (0.48) | CTSDALDH1A1KDM4ETDP1F2 | |
| SCHEMBL27311079 | 0.78 | PLAU (0.42) | PLAUCTSDALDH1A1GPR35TDP1 | |
| SCHEMBL27479915 | 0.78 | MAPT (0.39) | ALDH1A1GPR35TDP1HSD17B10L3MBTL1 | |
| SCHEMBL27482217 | 0.78 | HCAR3 (0.42) | ALDH1A1KDM4EHSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |