Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.87 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22834259 | 0.93 | CNR1 (1.00) | CNR1MAPTSMN1; SMN2EPHX2CYP2D6 | |
| SCHEMBL9818668 | 0.90 | CNR1 (0.70) | CNR1LMNASMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL300331 | 0.89 | CNR1 (0.72) | CNR1LMNASMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL9818691 | 0.87 | CNR1 (0.66) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818576 | 0.87 | LMNA (0.68) | CNR1LMNASMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL9818621 | 0.87 | CNR1 (0.66) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818715 | 0.86 | CNR1 (0.65) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818656 | 0.86 | MAPT (0.65) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818592 | 0.85 | CNR1 (0.63) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9818721 | 0.85 | CNR1 (0.63) | CNR1LMNAMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |