Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899573 | 0.82 | PGR (0.54) | PGRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL13189260 | 0.81 | MAOB (0.45) | PGRTAAR1MEN1KMT2ATAS1R3 | |
| SCHEMBL8501358 | 0.81 | PGR (0.53) | PGRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL24049723 | 0.80 | PGR (0.56) | PGRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL12165908 | 0.80 | KDM4E (0.50) | MEN1KMT2ATAS1R3TAS1R1KDM4E | |
| SCHEMBL14027797 | 0.78 | PGR (0.54) | PGRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL14134813 | 0.78 | KDM4E (0.44) | PGRKMT2ATAS1R3TAS1R1KDM4E | |
| SCHEMBL17885772 | 0.77 | PDCD1 (0.49) | PGRKDM4EMAPTALDH1A1MTNR1A | |
| SCHEMBL17859653 | 0.76 | HPGD (0.49) | KMT2AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL30112562 | 0.76 | BACE1 (0.44) | KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053548-A | Containing hydroxy substituents; nervous system disorders | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |